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Trivia about Ghost Rider: Spirit of Vengeance.
- Eva Mendes turned down the option to reprise her role as Roxanne Simpson.
- The Ghost Rider's skull has been redesigned for this sequel. The new skull appears to be black and charred, indicating that the skull is actually on fire as opposed to the clean fleshless skull simply cloaked in fire in the previous film.
- Not screened in advance for critics.
- The flashing image of the "devil" is Jerry Springer.
- WILHELM SCREAM: at about 01:20:23 when a man is thrown out of his truck by Ghost Rider.
- Cameo: Mark Neveldine, Brian Taylor: In the sequence where Johnny Blaze (Nicolas Cage) is explaining the deal with the devil the film's directors are pictured shaking hands, while one of them is on fire. This mirroring the cover to Pink Floyd's album "Wish You Were Here."